PipeBio is a cloud-based bioinformatics platform tailored for scientists and bioinformaticians working on antibody and immune repertoire analysis. It supports BCR, TCR, VHH, scFv, and peptide sequence data, providing tools for automated NGS and Sanger sequence processing, liability annotation, clonotype-based clustering, visualization, and hit selection. Users can store sequences in a central database with rich metadata, perform antibody engineering and developability assessments, and connect experimental data for deeper analysis. Through integrations with ELN and LIMS systems and a robust REST API, PipeBio enables fully automated, end-to-end bioinformatics pipelines from raw repertoire data to prioritized candidate hits.